Mister No rescues the famous matador Paco "Jirara" Morales, a fighter for the rights of his Jirara Indian people, from kidnapping. The grateful matador invites Mister No to Pamplona for a vacation, where he will participate in the bullfight at the famous
Mister No is hired by anthropologist Prof. Ribeiro and his assistant Saraj Moraes to escort them to a mission in the Catrimani Indian village. In the village, they are greeted by a tribe afflicted with a mysterious disease...